University of Bucharest, Romania
University of Bucharest, Romania
University of Bucharest, Romania and University of Perpignan, France
State University of New York at Binghamton
Silvana Andreescu is the Egon Matijević Endowed Chair in Chemistry and Professor of Bioanalytical Chemistry at Clarkson. She received a PhD in Chemistry, from the University of Perpignan, France, and the University of Bucharest, Romania in 2002, and has been a member of the Clarkson faculty since 2005. Between 2003 and 2005 she was a NSF-NATO postdoctoral fellow at the State University of New York at Binghamton. She is the recipient of a French Government Graduate Fellowship, a NATO-NSF Postdoctoral Fellowship, the NSF-CAREER Award, the John W. Graham Faculty Research Award, the Research Excellence Award and a Member of the Million Dollar Club at Clarkson University, reflecting funds received for sponsored research. In her research lab she has worked with and mentored over 15 graduate students, 4 post-doctoral fellows, 10 international visiting researchers, including a Fulbright Fellow, 3 high school teachers and over 50 undergraduates. She is committed to the success of her students and fellow researchers, many of whom are continuing their education at top graduate institutions or have secured rewarding positions in industry or academia.
- biomolecular recognition of nanoscale materials
- technologies for the immobilization of enzymes and biomolecular receptors
- single-molecule electrochemistry
- microelectrochemical probes for investigations of molecular mechanisms in biological systems
- portable nanoparticle-based assays for food analysis and environmental monitoring
- printable paper-based biosensors and field portable instrumentation
Current Research
Our research interests are in the areas of bioanalytical chemistry, electrochemistry, bionanotechnology, biosensing and environmental nanotechnology. We use modern spectroscopic and electrochemical instrumentation to study molecular level interactions of nanoscale materials, and we design devices that are inexpensive, easy-to-use and have the required detection sensitivity and selectivity for routine applications. Examples of our research projects include:
- field tests that change color within minutes when exposed to toxic chemicals, allowing testers to immediately detect the presence of harmful contaminants in food and environmental samples
- microelectrodes which allow us to study single molecules and measure physiological biomarkers
- electrochemical investigation of engineered nanoparticles and their interactions
New sensing technologies accessible to a broad range of users can substantially improve our measurement capabilities and generate scientific and technological advances for improving the quality of our environmental and, in essence, the quality of human life.
These projects provide students with the opportunity to learn methods for materials characterization, study biomolecular recognition, design their own devices and perform analytical characterization and measurements, all in an effort to address relevant scientific and engineering challenges. Research spans the traditional boundaries of chemistry, materials, biomolecular science and engineering disciplines.
- Arab-American Frontiers Fellow, National Academies of Sciences, Engineering and Medicine, 2017
- Research Excellence Award, Clarkson University, 2014
- John W. Graham Jr. Faculty Research Award, Clarkson University, 2011
- NSF-CAREER Award, National Science Foundation (NSF), 2010
- Invited professor, Technological Institute, University of Perpignan, Perpignan, France, 2007
- NSF-NATO Postdoctoral Fellowship Award, NSF, 2003–2004
- EGIDE-CNRS Research Scholarship, France, 2002
- BGF - French Government Doctoral Scholarship, University of Perpignan, France, 1999–2002
- Doctoral Scholarship: University of Bucharest, Faculty of Chemistry, Romania, 1999–2002
- European Community, TEMPUS-MS fellowship: Biosensors for Environmental Control, 1998
Andreescu, E. S., Othman, E. (2018). Us Patent No. US20180022604A1. FUNCTIONAL PLATFORM FOR RAPID CAPTURE AND REMOVAL OF NANOPARTICLES. https://patents.google.com/patent/US20180022604A1/en
Andreescu, E.S., Sharpe, E., Andreescu, D. (2015) US Patent No. US8969085B2. PORTABLE NANOPARTICLE BASED ASSAY FOR RAPID DETECTION OF FOOD ANTIOXIDANTS (NANOCERAC). https://patents.google.com/patent/US8969085
Andreescu, E.S., Ornatska, M., Ispas, C., Andreescu, D. (2014) US Patent No. US8691520B2 REAGENTLESS CERIA-BASED COLORIMETRIC SENSOR. https://patents.google.com/patent/US8691520B2/en
PEER-REVIEWED ARTICLES
Liu, X., Dumitrescu, E., Kumar, A., Austin, D., Goia, D., Wallace, K., Andreescu, E.S. (2019). Differential lethal and sub-lethal effects in embryonic zebrafish exposed to different sizes of silver nanoparticles. Environmental Pollution, 248, 627-634. https://doi.org/10.1016/j.envpol.2019.02.085
Sedki, M., Hassan, R.Y.A., Andreescu, E.S., El-Sherbiny, I.M. (2019). Online monitoring of biofilm formation using nanostructured electrode surfaces. Materials Science and Engineering: C, 100, 178-185. https://doi.org/10.1016/j.msec.2019.02.112
Karimi, A., Andreescu, E.S., Andreescu, D. (2019). Single particle investigation of environmental redox processes of arsenic on cerium oxide nanoparticles by collision electrochemistry. ACS Applied Materials & Interfaces, 11(27), 24725-24734. https://doi.org/10.1021/acsami.9b05234
Othman, A. Hayat, A., Andreescu, E.S. (2018). Eu-doped ceria as a nanoenzyme fluorescent probe for biosensing. ACS Applied Nano Materials, 1(10), 5722-5735, https://doi.org/10.1021/acsanm.8b01345
Andreescu, D., Kirk, K.A., Narouei, F.H., Andreescu, E.S. (2018) Electroanalytical aspects of single-entity collision methods for bioanalytical and environmental applications. ChemElectroChem, 5(20), 2920-2936. https://doi.org/10.1002/celc.201800722
Othman, A., Dumitrescu, E., Andreescu, D., Andreescu, E.S. (2018). Nanoporous sorbents for the removal and recovery of phosphorous from eutrophic waters: sustainability challenges and solutions. ACS Sustainable Chemistry & Engineering, 6(10), 12542-12561. https://doi.org/10.1021/acssuschemeng.8b01809
Mustafa, F., Andreescu, E.S. (2018). Chemical and biological sensors for food-quality monitoring and smart packaging. Foods, 7(10), 168. https://doi.org/10.3390/foods7100168
Bulbul, G., Hayat, A., Mustafa, F., Andreescu, E.S. (2018). DNA assay based on nanoceria as fluorescence quenches (NanoCeracQ DNA assay). Scientific Reports, 8(1), 2426. https://doi.org/10.1038/s41598-018-20659-9
Dumitrescu, E., Wallace, K., Andreescu, E.S. (2018). Real time electrochemical investigation of the release, distribution and modulation of nitric oxide in the intestine of individual zebrafish embryos, Nitric Oxide, 74, 32-38. https://doi.org/10.1016/j.niox.2018.01.002
Kirk, K.A., Othman, A., Andreescu, E.S. (2018). Nanomaterial-functionalized cellulose: design, characterization and analytical applications, Analytical Sciences, 34, 19-31. https://www.jstage.jst.go.jp/article/analsci/34/1/34_19/_pdf
Dumitrescu, E., Karunaratne, D., Babu, S.V., Wallace, K., Andreescu, E.S. (2018). Interaction, transformation and toxicity assessment of particles and additives used in the semiconducting industry, Chemosphere, 192, 178-185. https://doi.org/10.1016/j.chemosphere.2017.10.138
BOOKS
Hepel, M., & Andreescu, E.S. (Eds.). (2015). Oxidative Stress: Diagnostics, Prevention, and Therapy, Volume 2. Washington, DC: American Chemical Society. https://pubs.acs.org/doi/10.1021/bk-2015-1200
Hepel, M., & Andreescu, E.S. (Eds.). (2011). Oxidative Stress: Diagnostics, Prevention, and Therapy. Washington, DC: American Chemical Society.https://pubs.acs.org/isbn/9780841226838
Ram, M.K., Andreescu, E.S., Ding, H. (Eds.). (2011). Nanotechnology for Environmental Decontamination. New York, NY: McGraw-Hill. https://mhebooklibrary.com/doi/abs/10.1036/9780071702805