The University of Melbourne
The University of Melbourne
Prof. Devon A. Shipp is currently full Professor in the Department of Chemistry & Biomolecular Science, and Director of the Center for Advanced Materials Processing (CAMP). He completed a B.Sc. (Hons) in chemistry (1993), and then Ph.D. (1998) at the University of Melbourne (Australia). He then accepted the Bayer Postdoctoral Research Fellowship at Carnegie Mellon University (Pittsburgh, PA) with Prof. Kris Matyjaszewski. In 1999 he began his independent research career at Clarkson University. His research group focuses on new polymer chemistries, particularly radical polymerizations, nanocomposites, and degradable polymers for bio-related applications. He was a Fulbright Scholar in Slovenia in 2015, hosted by the Slovenian National Institute of Chemistry and the Faculty of Chemistry and Chemical Technology at the University of Ljubljana.
- Synthesis of polymers via radical and ionic polymerization
- Polymerization kinetics, controlled and living polymerizations
- Biomaterials; hydrogels; novel soft contact lens materials
- Synthesis and study of polymer–layered silicate nanocomposites
- Synthesis of block copolymers, polymer brushes, polymers attached to surfaces and particles
- Biodegradable network polymers for bone repair and drug delivery
- Synthesis and study of photon harvesting polymers, energy transfer in macromolecular systems
- Novel polymer-inorganic composites for photovoltaic applications (solar cells)
- Nano- and micro-particle surface modification, layer-by-layer approach to surface modification
Currently, my research group develops new polymer chemistries and materials that have potential in many applications, including various nanotechnologies and biomedical materials, and in areas that require polymers with high degrees of chemical and physical specificity. With wide-ranging capabilities in polymer chemistry, we have led the development of various novel materials, including synthetic (co-) polymers, nanoparticles, gels and nanocomposites.
In particular, there are three areas on which we are presently focused. The first is novel methods of synthesizing degradable polymer networks. We discovered that thiol-ene polymerizations are suitable for the synthesis of polyanhydrides, which can be made into promising surface-eroding materials and into polymer nanoparticles. These polymers have significant potential as drug delivery vehicles, within reconfigurable shape memory elastomer composites (SMECs), and self-healing polymers (SHPs). Second, we are also developing new methods for polymer particle synthesis based on water-borne thiol-ene/thiol-yne polymerization. These polymerizations leverage multiple “click” chemistry attributes so that colloidal particles can be made quickly and efficiently, with stoichiometric-controlled chemical functionality, uniform cross linking, and using an environmentally-benign reaction medium (water). This provides a significant opportunity to construct a new and transformational paradigm in polymer colloids, one that will result in sustainable, environmentally friendly, and high impact technologies. Lastly, we use our significant expertise in new radical polymerization methods, such as atom transfer radical polymerization (ATRP) and reversible addition-fragmentation chain transfer (RAFT) polymerization, to create polymers that exhibit novel and potentially highly useful thermal and mechanical properties. These have potential applications as shape memory polymers, adaptive nanocomposites, and surface-active agents (“surfactants”) that may be used in a variety of biomedical applications, such as drug delivery vehicles or contact lens care.
Fulbright Scholar,Ljubljana University & National Institute of Chemistry, Slovenia (January - July 2015)
Clarkson University Student Association Outstanding Teacher Award 2000-2001
Shipp, Devon. A. (2019). US Patent No. US010280263B1 ELASTOMERIC AND DEGRADABLE POLYANHYDRIDE BY STEP-GROWTH THIOL-ENE HOTOPOLYMERIZATION. US10280263B1
Linhardt, J.G., Shipp, D.A., Kunzler, J.F., Vanderbilt, D.P. (2012). US Patent No. US8100528B2 COATING SOLUTIONS COMPRISING SEGMENTED INTERACTIVE BLOCK COPOLYMERS. US8100528B2
Linhardt, J.G., Kunzler, J.F., Shipp, D.A. (2011). US Patent No. US8083348B2 Biomedical Devices. US8083348B2
Linhardt, J.G., Nunez, I.M., McGee, J.A., Hunt, J., Alton, M., Pavlovic, D., Shipp, D.A. (2011). US Patent No. US8043369B2 Biomedical Devices. US8043369B2
Linhardt, J.G., Shipp, D.A., Kunzler, J.F. (2011). US Patent No. US7942929B2 Coating Solutions Comprising Segmented Reactive Block Copolymers. US7942929B2
Polymer Colloids from Step-Growth Thiol-X Polymerizations
O. Z. Durham, D. A. Shipp
Polym. Rev., 2020, 60, in press.
Drug Delivery and Drug Efficacy from Amorphous Poly(thioether anhydrides)
B. L. Snyder, H. S. Mohammed, D. S. K. Samways, D. A. Shipp
Macromol. Biosci., 2020, 20, 1900377.
Cellular Delivery of Hoecsht 33342 Anticancer Drug from Crosslinked Poly(thioether anhydrides): A Cytotoxicity and Efficacy Study
H. S. Mohammed, D. S. K. Samways, D. A. Shipp
In Polymers in Therapeutic Applications, Y. Wang (Ed.), ACS Symposium Series 2020, Chapter 6, pages 63-77.
Composite Particles from Pickering-Stabilized Radical Mediated Thiol-Ene Suspension Polymerizations
K. J. Cassidy, O. Z. Durham, D. A. Shipp
Macromol. React. Eng. 2019, 13, 1800075.
Raman Microspectroscopy Study of the Hydrolytic Degradation of Polyanhydride Network Polymers
L. Bian, H.S. Mohammad, D.A. Shipp, P.J.G. Goulet
Langmuir, 2019, 35, 6387 – 6392.
Poly(N-vinlpyrrolidone)-Polydimethylsiloxane Amphiphilic ABA Triblock Copolymers
D. Pavlović, Q. Lou, J.G. Linhardt, J.F. Künzler, D.A. Shipp
J. Polym. Sci. Part A: Polym. Chem., 2017, 55, 3387-3394.
Effect of Chain Architecture on the Aqueous Solution Properties of Amphiphiliccopolymers: A study of poly(N-vinyl pyrrolidone-co-vinyl laurate)
K.A. Knapp, I.M. Nuňez, D.A. Shipp
Polymer, 2018, 141, 54-61.
Radical-Mediated Thiol-Ene Emulsion Polymerization
O.Z. Durham, D.V. Chapman, S. Krishnan, D.A. Shipp
Macromolecules, 2017, 50, 3, 773-783.
Polyanhydride Nanoparticles: Thiol-Ene ‘Click’ Polymerizations Provide Functionalized and Crosslinkable Nanoparticles with Tunable Degradation Times
O.Z. Durham, K.L. Poetz, D.A. Shipp
Aust. J. Chem., 2017, 70, 735-742.
Polyanhydrides: Synthesis, Properties and Applications
K.L. Poetz, D.A. Shipp
Aust. J. Chem., 2016, 69, 1223-1239.
Radical Mediated Thiol-Ene/Yne Dispersion Polymerizations
F. Alimohammadi, C. Wang, O.Z. Durham, H.R. Norton, C.N. Bowman, D.A. Shipp
Polymer, 2016, 105, 180-186.
Anhydride-Based Reconfigurable Shape Memory Elastomers
M.I. Lawton, K.R. Tillman, H.S. Mohammed, W. Kuang, D.A. Shipp, P.T. Mather
ACS Macro. Lett., 2016, 5, 203-207.
Quantitative and Qualitative Toxicological Evaluation of Thiol-Ene “Click” Chemistry-Based Polyanhydrides and Their Degradation Products
H.S. Mohammed, B.L. Snyder, D.S.K. Samways, D.A. Shipp
J. Biomed. Mater. Res. Part A, 2016, 104A, 1936-1945.