Skip to main content
Clarkson University Logo
  • Visit
  • Apply
  • Request Info
  • Give
  • Alumni
  • Parents
  • Intranet
  • About
    • President's Page
    • Board of Trustees
    • Administration
    • History & Facts
    • Accreditation
    • Accolades
    • The Clarkson Brand
    • Maps & Directions
  • Academics
    • Undergraduate Programs
    • Graduate Programs
    • Continuing & Professional Education
    • School of Arts & Sciences
    • Lewis School of Health Sciences
    • Reh School of Business
    • Coulter School of Engineering
    • Beacon Institute for Rivers and Estuaries
    • Institute for a Sustainable Environment
    • Institute for STEM Education
    • Academic Affairs
    • Student Achievement Services
    • Academic Calendar
  • Admissions
    • First-Year Admissions, Undergraduate
    • Transfer Admissions, Undergraduate
    • International Admissions, Undergraduate
    • Early College Program: The Clarkson School
    • Graduate School Admissions
    • Financial Aid
    • Apply Now
  • Campus Life
    • Office of Student Life
    • Student Clubs & Activities
    • Living on Campus
    • Campus Dining
    • Clarkson Ignite
    • Career & International Experiences
    • Explore the Region
    • Diversity, Equity & Inclusion
    • Student Health & Counseling
    • ROTC
    • Office of the Dean of Students
  • Research
  • Athletics
  • News
  • Search

CU • News & Events

Clarkson University Research Professors Published in Nature Communications

Release Date
Thursday March 23, 2023

Clarkson University Research Professors Kelsey Moody and Aaron Wolfe were recently published in the peer-reviewed, open access scientific journal Nature Communications with their article titled “A generalizable nanopore sensor for highly specific protein detection at single-molecule precision.”

nature communications logo

Moody, who is also the Founder and CEO of  Ichor Life Sciences, and Wolfe, Ichor’s Chief Science Officer, worked with six other researchers on the article, which focuses on the development of highly efficient molecular diagnostics. 

Ichor studies fundamental mechanisms of aging to develop new classes of drugs dedicated to helping people live longer, healthier lives. In collaboration with the Lewis School for Health Sciences, Ichor has expanded to occupy offices and wet laboratory space in Peyton Hall on Clarkson’s downtown campus.

“Molecular diagnostics are used to monitor onset, progression, and regression of disease – even when patients are not necessarily symptomatic,” Moody explained. “Existing technologies require relatively large quantities of blood and many diagnostic tests have high limits of detection. You need to have a high burden of virus in your bloodstream to detect it, for example. This technology utilizes a nanopore system that can be tuned to detect any protein of interest with a single-molecule detection limit.”

Wolfe said the research has the potential to be a hallmark for all molecular diagnostics modalities in the future.

 “Imagine the ability to detect very limited analytes specifically in minute volumes of complex fluid like liquid biopsies or blood,” he said. “This is an amazing advancement for protein detection broadly and has potential as a tunable molecular diagnostic tool.”

Wolfe, who has been working in the field of single molecule protein sensing for nearly 20 years, believes this publication highlights the cohesive power of the partnership between Clarkson and Ichor. 

“I believe that our ethos at Clarkson and that of Ichor is that science is a team sport and that we should be working with as many folks as possible highlighting the various strengths of our respective organizations,” Wolfe said. “We love collaborating with various professors and teams with our Clarkson graduate students to allow them to have the deepest experience for their respective degrees. We are really excited for the work that is being done now that will be led by our students.”

The published article can be found at nature.com/articles/s41467-023-36944-9.
 

As a private, national research university, Clarkson is a leader in technological education and sustainable economic development through teaching, scholarship, research and innovation. We ignite personal connections across academic fields and industries to create the entrepreneurial mindset, knowledge and intellectual curiosity needed to innovate world-relevant solutions and cultivate the leaders of tomorrow. With its main campus located in Potsdam, N.Y., and additional graduate program and research facilities in the New York Capital Region, Beacon, N.Y., and New York City, Clarkson educates 4,600+ students across 95 rigorous programs of study in engineering, business, the arts, education, sciences and health professions. Our alumni earn salaries that are among the top 2.5% in the nation and realize accelerated career growth. One in five already leads as a CEO, senior executive or owner of a company. To learn more about Clarkson University, go to www.clarkson.edu.


Photograph for media use is available at:
/sites/default/files/media/image/2023-03/nature-communications.png

Photograph Size:
Width: 225px
Height: 225px

News directors and editors: For more information, contact Jake Newman, Director of Media Relations, at 315-268-6764 or jnewman@clarkson.edu.

Schools at Clarkson

  • Graduate School
  • School of Arts & Sciences
  • David D. Reh School of Business
  • Wallace H. Coulter School of Engineering
  • Earl R. and Barbara D. Lewis School of Health Sciences
  • Institute for a Sustainable Environment
  • Early College Program: The Clarkson School
  • Institute for STEM Education
  • Beacon Institute for Rivers and Estuaries

Highlights of Excellence

  • Career Center
  • Honors Program
  • ROTC
  • Student Projects for Engineering Experience and Design (SPEED)
  • Student Success Center
  • Writing Center

Research & Innovation

  • Clarkson Center for Complex Systems Science (C3S2)
  • The Center for Advanced Materials Processing (CAMP)
  • Center for Air and Aquatic Resources Engineering & Science (CAARES)
  • Center for Identification Technology Research (CITeR)
  • The Center for Rehabilitation Engineering, Science & Technology (CREST)
  • NYS Center of Excellence in Healthy Water Solutions
  • The Shipley Center for Innovation
  • Clarkson Ignite
  • University Libraries

Clarkson University

8 Clarkson Ave., Potsdam, New York 13699 315-268-6400
80 Nott Terrace, Schenectady, NY 12308 518-631-9831
199 Dennings Ave., Beacon, New York 12508 845-838-1600
Take a Virtual Tour

Organizational Chart
© 2023 by Clarkson University | Web Accessibility Assistance

  • Human Resources • Giving • Bookstore
  • CARES Act Reports & Consumer Information Disclosures (HEOA)
  • Act on Legal & Moral Concerns