Prof. Christopher Bellona
6
President's Report
#36
Faculty receiving significant research
awards in the national universities
category, Washington Monthly 2012.
IN THE
NAT ION
Prof. Diego Nocetti
Monitoring Neurotransmitters During a Stroke
Working with neurophysiologists and medical doctors at Dartmouth Medical School,
Chemistry & Biomolecular Science Professor Silvana Andreescu and her team are developing
sensing technology to monitor chemical substances associated with neural signaling and
function during oxygen deprivation in the brain.
The technology will provide real-time
assessment of the changes and provide answers to
fundamental questions related to the biochemical
and cellular events involved in conditions of
oxygen deprivation, such as stroke or other
neurological event.
With funding from the NIH, the new
sensor under development in the Clarkson
laboratory is designed to function well in
low-oxygen environments and provide a new
method for studying the neurobiology of these
neurotransmitters in hypoxic conditions. The
research will also facilitate further understanding
of glutamate and lactate neurotransmission in a
variety of other neurological disorders in which
oxygen is restricted.
The Economics of Uncertainty
How are rates of savings affected by perceived risk or uncertainty in the marketplace?
Diego C. Nocetti, an associate professor of economics and finance, is an expert in the
economics of uncertainty, with particular emphasis on the development of theoretical models
that analyze both positive and normative aspects of decision-making under uncertainty.
In one line of his research, Nocetti explores the theory of precautionary saving, quantifying
the strength by which rates of saving respond to different sources of uncertainty.
“Understanding how consumers react when faced with a more uncertain economic
environment is of critical importance for public policymaking,” he says. “This research has
implications for some of the most important debates currently
going on in Washington, D.C., from Social Security reform to
the effect of insurance requirements under Obamacare.”
Nocetti’s research has been published in leading academic
journals including, the
Journal of Money Credit and Banking
, the
Journal of Economic Dynamics and Control
,
Health Economics
,
Economics Letters
, the
B.E. Journal of Economic Analysis and Policy
,
and the
Journal of Applied Economics
.
His article "Properties of the Social Discount Rate in
a Benthamite Framework with Heterogeneous Degrees of
Impatience," published in
Management Science
, was awarded the
Finance and Sustainability European Research Award.
Nocetti’s most recent article, “On Multivariate Prudence,”
published in the
Journal of Economic Theory
(2013) and
written with colleagues from the University of Paris, looks at
precautionary saving motives and social discounting in the
presence of multiple sources of risk.
F
Prof. Silvana Andreescu (center) with graduate students Anastasia C.H. Scangas
and Rifat E. Ozel.
Research professor Alisa Woods and graduate student Armand Ngounou Wetie.
$500K for Innovative Water Treatment Methods
Last summer, Clarkson researchers and the Southern Nevada
Water Authority received a $500,000 grant from the Environmental
Protection Agency.
Civil & Environmental Engineering Assistant Professor
Christopher Bellona is the principal investigator on the project. He
is working with Clarkson co-investigators Civil & Environmental
Engineering Professor Thomas M. Holsen and Chemical &
Biomolecular Engineering Assistant Professor Selma Mededovic, and
Eric Dickenson, project manager for the Southern Nevada
Water Authority.
The team is developing an integrated water treatment method
using membrane technologies combined with an advanced oxidation
process to remove emerging organic contaminants from drinking
water. The ultimate goal is to create a water treatment process for small
treatment systems with the means to simultaneously remove particles,
microbial pathogens, organic carbon and regulated and unregulated
organic contaminants.
Identifying Biomarkers for Autism
According to the Centers for Disease Control and Prevention, about one in 88 children in the
United States has autism.
Yet, there is currently no medical test to diagnose the condition.
Clarkson researchers Alisa Woods and Costel Darie are hoping to change that. The two
are working to identify biomarkers for
autism spectrum disorders in blood
and saliva taken from children. They
hope to find proteins that could help
diagnose the condition early on and
provide clues to what causes autism.
“Currently, children are
diagnosed based on behavioral
symptoms and this generally occurs
around the age of two or three,” says
Woods, a cognitive neuroscientist
and research assistant professor
of chemistry and biomolecular
science. “This delay in treatment
is significant and has implications
for a child’s overall development.
Confirming a biological basis for
autism will also help reduce the stigma that surrounds it.”
In the Laboratory for Proteomics and Biochemistry, Costel Darie and his researchers
are taking blood and saliva samples from children diagnosed with autism and from control
subjects. The researchers separate the proteins and then, using mass spectrometry, are able
to measure levels of hundreds of proteins at a time.
Their work is already yielding some results. The team has identified some promising
protein markers that could form the basis of a diagnostic test. They have submitted this
work to
Molecular Psychiatry
, and have also published research describing the approach
in the
Journal of Molecular Psychiatry
and the
Journal of Cellular and Molecular Medicine
.
In 2012, Alisa
Woods received
the Hanse Prize
for Psychiatry
for her
neuropsychiatric
research on
biomarkers in
psychiatry.
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