CAMP Annual Report: Page 10
Portable Ceria Nanoparticle-Based Assay for Rapid Detection of Food Antioxidants
Professor Silvana Andreescu (of Clarkson University’s Department of Chemistry and Biomolecular Science) and her group have developed and characterized a portable nanoparticle based-assay, similar to a small sensor patch, for the rapid and sensitive detection of food antioxidants. See Figure 2. In recent years, much attention has been focused on antioxidants because of their supposed ability to promote good health and slow down the ageing process, etc. The team’s assay is based on the use of immobilized ceria nanoparticles, which change color after interaction with antioxidants by means of redox and surface chemistry reactions. See photo. The sensor has been tested for the detection of common antioxidant compounds including ascorbic acid, gallic acid, vanillic acid, quercetin, caffeic acid, and epigallocatechin gallate. Also its function has been successfully applied for the assessment of antioxidant activity in real samples (teas and medicinal mushrooms). The colorimetric response was concentration dependent and based on the antioxidant involved. The sensor performed favorably when compared with commonly used antioxidant detection methods. This new assay is particularly appealing for remote sensing applications, where specialized equipment is not available, and also for high throughput analysis of a large number of samples. More information about this work is available in the journal Analyst (2013, 138, 249-262).
Figure 2: Multisensor Array for Field Analysis of Antioxidants
In addition Erica Sharpe, a Ph.D. student for Professor Andreescu, won the Young Investigator's Award at the Linus Pauling Institute's Diet and Optimum Health conference in Corvallis, Oregon, for similar work. She carried out green tea research during a pre-doctoral fellowship at Bastyr University in Washington State during the fall of 2012.
Her studies showed how well different varieties of green tea were able to maintain high levels of antioxidants after reuse.
Recently, Clarkson Professor Vladimir Privman and coworkers published their results for modeling the sintering of nanoparticles (that are of interest in applications developed by their CAMP colleagues, specifically, Professor Dan V. Goia). The Royal Society of Chemistry Editors selected this work to be highlighted as the cover article for the journal CrystEngComm (Volume 15, Number 36, 28 September 2013, 7131-7382).
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Senior University Professor Richard Partch, of Clarkson’s Center for Advanced Materials Processing, was in Spain for two weeks in September as an invited guest at the EDIBON Company in Madrid, an invited speaker and session chair at the 3-day 2013 International NANOSMAT Conference in Granada, and as a presenter of a 1.5 hour Short Course. He toured the facilities and interacted with former Clarkson research associates Manuel Ocana and Luis Perez at the Instituto de Sciencia de Materiales de Sevilla. EDIBON Company manufactures a wide variety of computer interfaced apparatus and instrumentation designed specifically for teaching in technology laboratories.
About 800 international scientists and engineers attended the three day NANOSMAT Conference which exposed some of the best nanotechnology being investigated on the planet. Professor Partch’s two presentations were titled “Thermal Management of Nanoparticle-Filled Composites” and “Colloids for Medical Therapy: Nanoparticle Approaches for Chemical Overdose and for Cancer Treatment.” The session he chaired was titled “Nanomaterials: Synthesis, Characterization and Applications.” His Short Course presented in Sevilla was titled “Enhancing Particle Applications by Surface Modification.”
Senior University Professor Richard Partch displays his poster at the St. Lawrence County National Manufacturers Day Event organized by NNY CITEC.
In another venue Professor Partch displayed a poster and was luncheon speaker discussing the diverse technology research and development opportunities in engineering, math, and science, taking place at Clarkson. This special activity was held in October at the St. Lawrence County National Manufacturers Day Event organized by NNY CITEC for NNY pre-college teachers, school councilors and some BOCES students in high school “Tech Prep” programs. Industry spokespersons were from Alcoa, Ansen, Corning and Curran Companies. Partch spoke about how R&D is the first step in a manufacturing process and that no successful person in manufacturing achieves by working alone but that teamwork is essential.