CAMP Annual Report: Page 6
Professor Egon Matijevc’, Editor of New Book: Medical Applications of Colloids
Professor Egon Matijevic' , the Victor K. LaMer Chair of Colloid and Surface Science at Clarkson University, is Editor of the new book Medical Applications of Colloids published by Springer in 2008. In the Preface, he mentions that the important role of finely dispersed matter and surfaces in medicine is not always fully understood and appreciated. Matijevic’ also states that fine particles (size range of several nanometers to several micrometers) have a tremendous effect on our lives because they can be beneficial or detrimental to our well-being. This volume provides insight into significant topics in colloid and surface science that relate to medical applications.
The book chapters and their authors are as follows.
“Colloids as Light Scattering and Emission Markers for Analysis of Blood” by Olavi Siiman
“Medical and Technological Application of Monodispersed Colloidal Silica Particles” by Herbert Giesche
“Pharmaceutical Applications of Finely Dispersed Systems” by H. William Bosch
“Transport, Deposition, and Removal of Fine Particles: Biomedical Applications”
by Goodarz Ahmadi and John B. McLaughlin (both of Clarkson University)“XPS Analysis of Biosystems and Biomaterials” by Michel J. Genet, Christine C. Dupont-Gillain, and Paul G. Rouxhet
Professor Matijevic', an internationally recognized colloid chemist, was recently named an Honorary Distinguished Academic Appointee to the medical staff of the Canton-Potsdam Hospital by its board of directors. This prestigious honor, a first of its kind for the hospital, was given for his ground-breaking research relating to medical applications. His ability to synthesize minute particles with precise sizes and composition has special relevance to the medical field, because it assists pharmaceutical manufacturers in developing drug formations that can be delivered to patients more quickly to relieve pain or the cause of ailment.
Clarkson University hosted a series of receptions throughout the country in 2007 to provide Matijevic’s friends, colleagues and former students an opportunity to celebrate his 50 year milestone as a teacher, scientist and mentor.
Professor Matijevic' was born and educated in Croatia. He began his teaching career at Clarkson in 1957. In addition to numerous Honorary Ph.D.s and citations, he is the only individual to receive all three major awards of the American Chemical Society in his field of Colloid Chemistry. He is also the recipient of the Graham Award, the highest prize bestowed by the German Colloid Society, the oldest in the world.
From left: Clarkson University Provost Thomas Young, Distinguished University Professor /CAMP Director S.V. Babu, Goldwin Smith Professor Emeritus Jerrold Meinwald (of Cornell University in Ithaca, New York) Clarkson University President Anthony Collins, and Professor Egon Matijevic', the Victor K. LaMer Chair of Colloid and Surface Science at Clarkson University.
Goldwin Smith Professor Emeritus Jerrold Meinwald Presents Shipley Distinguished Lectures at ClarksonGoldwin Smith Professor Emeritus Jerrold Meinwald (of Cornell University in Ithaca, New York) presented the Fourteenth Shipley Distinguished Lectureship at Clarkson University. His talks titled “Violence, Sex, and Drugs in the World of Insects” and “Exploring the Chemistry of Biotic Interactions,” were sponsored by Clarkson’s Center for Advanced Materials Processing (CAMP) with support from the Shipley Family Foundation.
Self Healing Materials
A team led by Professor Igor Sokolov is developing self-healing materials for a U.S. Army funded project. They are preparing special healing glass capsules (nanoporous silica capsules containing epoxy components) embedded in a polymer matrix. When this matrix is fractured, a crack propagates and ruptures the capsules. Healing glue leaks out into the crack, seals, and cures the crack. This repairs the crack, and to some extent recovers the mechanical integrity of the polymer. CAMP Professors John Moosbrugger and David Morrison are developing testing methods to reveal the recovery of the mechanical properties in self healing materials. In addition CAMP Professors Ratneshwar Jha, Cetin Cetinkaya, Goodarz Ahmadi, and Igor Sokolov are studying the mechanical properties of the self-healing materials to provide a fundamental knowledge of the mechanical behavior of undamaged and healed materials. A multi‑scale model will be used to predict the effects of healing fiber concentration, aspect ratio, and modulus on the mechanical properties of the composite material. The response of self‑healing composite structures to quasistatic and dynamic loads will be investigated. The modeling will determine stress/strain concentrations, failure mechanisms, stress wave propagation, and healing efficiency.
Self-Assembly of Stable Organic Monolayers in Ionic Liquids for Sensor Applications
Self-assembled monolayers (SAMs) of alkanethiols have a wide range of applications in chemical and electrochemical sensors. CAMP Professor Dipankar Roy is studying fabrication of these SAMs, as well as their electrochemical properties in room temperature ionic liquids (ILs). In the solution-based approach, typically these SAMs are formed on gold film substrates in ethanol or other similar (often prone to vaporize) solvents. The SAMs formed in ILs tend to exhibit higher structural integrity and stability than their counterparts formed in the low viscosity solvents. The high viscosity and the relatively large ions of ILs restrict the extent of diffusion limited solvent-incorporation (defect formation) in the SAMs formed in ILs. Furthermore, the electrochemical stability of these SAMs formed in ILs can also be substantially improved by using an IL (as opposed to aqueous) environment to support the surface electrochemistry for sensor operation. The considerably wider electrochemical windows of ILs compared to those of aqueous electrolytes provide this latter feature of sensor operation in IL media. Thus, incorporation of ILs in SAM-engineering can offer several potential advantages for sensor applications. Professor Roy's group is exploring these IL-SAM systems by combining the techniques of surface plasmon resonance and electrochemical impedance spectroscopy. More information about this group's research can be found at: