CAMP Sponsors Seventh International Symposium on Chemical-Mechanical Polishing (CMP)

CAMP sponsored its seventh very successful International Symposium on Chemical-Mechanical Polishing. The four-day symposium/workshop held (August 11 - 14, 2002) at the Hilton Resort in Lake Placid, New York, attracted over 100 participants from around the world. Attendees were from the United States, Japan, and other Countries. This meeting was co-chaired by Dr. Manabu Tsujimura (Ebara Corporation), Dr. Dan Heenan (IBM), and Vice Provost/CAMP Director S.V. Babu. It included presentations by industrial and university representatives and a poster session displaying CAMP's research activities on CMP.

   

 

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THIN FILMS AND COATINGS

Deposition of Diamond Films, Aluminum Alloy Solidification, and Contact Angle Measurements

Professors Liya L. Regel and William Wilcox have continued research on the deposition of diamond films on a variety of substrates, including those of interest to Kodak and Corning. They are utilizing a new, simpler, less expensive method than has been used previously. There are many potential applications.

Professors Regel and Wilcox are also working with scientists from the Ioffe Physical Technical Institute in St. Petersburg, Russia to determine the influence of levitation and centrifugation on the microstructure of aluminum alloys.

They have developed the capability of measuring contact angles at high temperature, and have been applying it to molten semiconductors and to liquids of interest to Osram Sylvania.

PARTICLE TRANSPORT, DEPOSITION AND REMOVAL

Inhalation Drug Delivery and Lung Deposition

Clarkson Distinguished Professor Goodarz Ahmadi, in collaboration with Dr. Han and Dr. Greenspan of Dura Pharmaceuticals, is studying powder dispersion in inhalation drug delivery systems. He is also analyzing the dispersion and breakup of powder under the action of a strong shear field. The results provide insight into the design of drug delivery systems.

Three-Phase Slurry Reactors

Professor Ahmadi is collaborating with scientists at the Department of Energy in modeling a three-phase slurry reactor for synthetic liquid fuel production from coal. One main objective is to develop an advanced computational capability for predicting the transport and processing of three-phase (liquid - gas - solid) slurry reactors. The specific objective is to develop an accurate and reliable computational model for predicting the process parameters using the extended thermodynamically consistent anisotropic theories of multiphase flows.

Fundamentals of Natural Gas and Species Flow from Hydrates Dissociation

The primary goal of Professor Ahmadi's project is to provide a fundamental understanding of flow conditions of hydrate dissociation products in consolidated and unconsolidated sediment. He and his group will develop semi-analytical computational models to be used as tools for safety related issues. These include predicting the rate of natural gas pressure buildup during drilling in a hydrate reservoir, the nature of gas and water flows in the reservoir after hydrate dissociation, and the potential for sea floor instability. Availability of such an understanding, detailed experimental data and a computational tool are crucial to the future development of technology for economical and safe natural gas production from hydrates in the 21st Century.

Hot-Gas Filtration

Professor Ahmadi is studying the process of hot-gas filtration for applications to clean coal technology. In this project, the performance of ceramic candle-filters for hot-gas cleaning is being studied. Research results show that small particles (less than a micron) deposit rather uniformly in the filter vessel, while the larger particles deposit non-uniformly. This work has significant implications in designing future industrial scale hot-gas cleaning systems.

Electrohydrodynamic Flows During Corona Discharge

Professor Ahmadi and his students, along with Dr. Fan of Xerox, are studying electrohydrodynamic flows during corona discharge in an electrophotographic machine (e.g., printers and copiers). They developed a computational model for analyzing gas electrohydrodynamic flows and the transport and deposition of charged toner particles in the presence of a strong electric field. They showed that electrohydrodynamics could strongly affect the transport and deposition of small particles in corona devices. In addition, Professor Ahmadi is collaborating with Dr. Sadasivan of Kodak on a project about the aerodynamic focusing of nanoparticle beams.

COLLOIDAL DISPERSIONS AND PROCESSING

Novel Methods for Liposome Synthesis

Professor Yuzhuo Li and his graduate students, Nicole Heldt and Fadwa Odeh, are exploring new methods for the preparation of liposome with controlled particle size and size distribution. The pharmaceutical industry utilizes liposomes for a variety of applications such as drug delivery and diagnostic imaging. For drug delivery systems both polymer stabilized liposome systems (PSLS) and non-polymer stabilized (conventional) liposome systems (NPSLS) are beneficial. In collaboration with Adjunct Professor Robert Laughlin and Research Associate Professor Chris Brancewicz, Li's group is systematically investigating the effect of a hydrotrope on the phase behavior of lipids and its impact on the liposome properties. As a world renowned scientist in phase science, Professor Robert Laughlin, brought a tremendous wealth of expertise to the Chemistry Department and CAMP at Clarkson. His applied physical science lecture series is available for viewing at http://media.clarkson.edu. The goal of this research is to develop an optimized liposome system for drug delivery and medical diagnostic applications.

Polymers and Biomedical Work

Professor Anja Mueller, of Clarkson University's Department of Chemistry, is carrying out research that makes use of polymers in biomedical work. Her postdoctoral research was on liposomes as drug delivery agents. It included the characterization of controlled release upon a light signal, liposome fusion with membranes, and characterization of the behavior of liposomes in a cell culture. Professor Mueller's current and future research projects include the development of a biological fuel cell for medical sensors, synthesis of hydrophilic polymers with enzymes and their surface characterization for the development of a heart valve coating and other biomedical applications. In addition she will investigate the use of polymers for biosensors and waste water treatment. Professor Mueller has a Provisional Patent 60/347,012 (Anja Mueller and Maciej Markowski: "Low Thrombogenic Coating for Intravascular Devices."). Her recent publication is : Mueller, A. and O'Brien, D.F., "Polymerization of Mesophases of Hydrated Amphiphiles," Chemical Reviews , 102, 727 (2002).

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