Chemistry & Biomolecular Science
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Silvana Andreescu BIOSEM Group |
Educational Background
Ph.D. University of Bucharest, Bucharest, Romania (Analytical Chemistry) and
University of Perpignan, Perpignan, France (Agrochemistry)
NATO-NSF Postdoctoral Fellowship, State University of New York at Binghamton
Research Interests
Biosensors for environmental and clinical monitoring (e.g. implantable enzyme microbiosensors for in vivo and in vitro monitoring of neurological activity for dopamine, serotonin, glutamate, lactate, glucose and reactive oxygen species - applications in neurobiology and ischemia sensing); Biomimetic materials for biosensors manufacturing; Antioxidant and cytotoxic activity of engineered nanomaterials and potential in vivo therapeutic applications; Microencapsulation techniques of biological material for uses in biotechnology, environmental bioremediation and in fermentation/hydrolysis processes, in the production of bioethanol from cellulosic biomass.
Selected Publications (last 4 years, *designates undergraduate authors):
1. C. Ispas, D. Andreescu, A. Patel,* D. Goia, S. Andreescu, K. Wallace, Toxicity and developmental defects of different sizes and shape nickel nanoparticles in zebrafish, Environmental Science and Technology, ASAP article, 2009. DOI: 10.1021/es9010543.
2. S. Andreescu, J. Njagi, C. Ispas, M. Ravalli, Applications of advanced nanomaterials for environmental monitoring, J. Env. Monitoring, 11, 2009, 27–40.
3. C. Ispas, I. Sokolov, S. Andreescu, Enzyme functionalized mesoporous silica for bioanalytical applications,Anal. Bioanal. Chem., 393, 2, 2009, 543-554.
4. M. Ornatska, M. Ganesana, S. Andreescu, Biosensors: Toxicity Monitoring, in Encyclopedia of Industrial Biotechnology, Wiley, In press, 2009.
5. L Stanciu, Y.-H. Won, M. Ganesana, S. Andreescu, Magnetic Particles-Based Hybrid Platforms for Bioanalytical Sensors, 9, Sensors, 2009, 2976-2999.
6. N. Sazonova, J.I. Njagi, Z. Marchese,* M. Ball,* S. Andreescu, S. Schuckers, Detection and prediction of concentrations of neurotransmitters using voltammetry and pattern recognition, IEEE Engineering in Medicine and Biology, 2009.
7. J. Njagi, C. Ispas, S. Andreescu, Mixed Ceria Based Metal Oxides Biosensor for Operation in Oxygen Restrictive Environments, Anal. Chem., 80, 2008, 7266-7274.
8. C. Ispas, J. Njagi, M. Cates,* S. Andreescu, Electrochemical Studies of ceria as electrode material for sensing and biosensing applications, J. Electrochem. Soc., 155(8), 2008, F169-F176.
9. S. Andreescu, L.A. Luck, Studies of the Binding and Signaling of Surface-immobilized Periplasmic Glucose Receptors on Gold Nanoparticles: A Glucose Biosensor Application, Anal. Biochem., 375, 2008, 282-290.
10. S. Andreescu, J. Njagi, C. Ispas, Nanostructured Materials for Enzyme Immobilization and Biosensors, in “The New Frontiers of organic and composite nanotechnology” Ed. Victor Erokhin, Manoj Kumar Ram, Ozlem Yavuz, Elsevier (ISBN 978-0-0804-5052-0), 2008, 355-394.
11. J. Njagi, S. Andreescu, Stable enzyme biosensors based on chemically synthesized Au-polypyrrole nanocomposite, Biosens. Bioelectron., 23, 2, 2007, 768-775.
12. G. Istamboulie, S. Andreescu, J-L Marty, T. Noguer, Highly sensitive detection of organophosphorus insecticides using magnetic microbeads and genetically engineered acetylcholinesterase, Biosens. Bioelectron., 23, 4, 2007, 506-512.
13. N. Salem, S. Andreescu, E. Kulla, P. Zuman, Existence and Reactivity of Three Forms of Orthophthalaldehyde in Aqueous Solutions. Polarographic, Voltammetic and Spectrophotometric Study, J. Phys Chem. A.,111, 2007, 4658-4670
14. D. Goia, D. Andreescu, S. Andreescu,Integration of Nanomaterials into the Undergraduate Chemistry Curriculum: Synthesis and Characterization of Gold Nanoparticles, Chem. Educator, 12, 4, 2007, 256-259.
15. J. Njagi, J. Warner,* S. Andreescu, A Bioanalytical Chemistry Experiment for Undergraduate Students: Biosensors Based on MetalNanoparticles, J. Chem Edu. 84. 7, 2007, 1180-1182.
16. M. Sheban, M. Abu-Dalo, A. Ayman, S. Andreescu, Effect of benzotriazole derivatives on corrosion of steel in simulated concrete pore solutions, Anti-corrosion methods and materials, 54, 3, 2007, 135-147 (2008 Outstanding Paper Award by Emerald LiteratiNetwork).
17. S. Andreescu, J.-L. Marty, Twenty years research in cholinesterase biosensors: From basic research to practical applications, Biomolecular Engineering, 23 (1), 2006, 1-15.
Patents
1. B.J. Frederick, E.S. Andreescu, P.A. Christiansen, Co-immobilization of D-xylose isomerase and Saccharomyces cerevisiae for the efficient production of fuel ethanol, US patent application, US 60 / 924,967, June 2008.
2. E.S. Andreescu, J. C. Leiter, J. S. Erlichman, A method of neuroprotection from oxidant injury using metal oxide nanoparticles, US Provisional Patent Application 611055926, September, 2008.
Research Assistant Professor
- Dr. Maryna Ornatska
Current Graduate Students
- John Njagi
- Cristina Ispas
- Malli Ganesana
- Emrah Ozel
- Erica Sharpe
Graduate students - alumni:
- Brian Frederick, MS 2009, now at the University of Pennsylvania
- Matthew Ravalli, MS 2009, now at SUNY Albany
Visiting Scientists
- Ramiz Kassir
Current Undergraduate Students
- Megan Himmler
- Sejal Patel
- Michael Ball
- Zachary Marchese
- Anastasia Scangas
- Daniel VanDorn
- Jessica Newer
- Amanda Koenck